(1S)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanamine

(1S)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanamine - Names and Identifiers

Name	(R)-1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHYLAMINE HCL
Synonyms	S-MBT-PEM (S)-1-(3,5-BIS(TRIFLUOROMETHYL)PHENYL)ETHANAMINE (S)-1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHYLAMINE (1S)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanamine (1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethanamine (S)-1-[BIS-3,5-(TRIFLUOROMETHYL)PHENYL]ETHYLAMINE (S)-1-(3,5-bis(trifluoromethyl)phenyl)ethan-1-amine (S)-ALPHA-METHYL-BIS-3,5-TRIFLUOROMETHYLBENZYLAMINE (R)-1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHYLAMINE HCL Benzenemethanamine, α-methyl-3,5-bis(trifluoromethyl)-, (αS)- [(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl]ammonium chloride
CAS	127733-40-8
InChI	InChI=1/C10H9F6N.ClH/c1-5(17)6-2-7(9(11,12)13)4-8(3-6)10(14,15)16;/h2-5H,17H2,1H3;1H/t5-;/m1./s1

(1S)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanamine - Physico-chemical Properties

Molecular Formula	C10H9F6N
Molar Mass	257.18
Density	1.327±0.06 g/cm3(Predicted)
Boling Point	60/14mm
pKa	8.39±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2–8 °C

(1S)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanamine - Risk and Safety

Risk Codes	22 - Harmful if swallowed
Hazard Note	Irritant

(1S)-1-[3,5-Bis(trifluoromethyl)phenyl]ethanamine - Introduction

(S)-1-[3,5-bis (trifluoromethyl) phenyl) ethylamine is an organic compound with the chemical formula C10H12F6N2. It has the following properties:

1. Appearance:(S)-1-[3,5-bis (trifluoromethyl) phenyl) ethylamine is a colorless liquid.
2. Solubility: It can be dissolved in a variety of organic solvents, such as methanol, ethanol and dichloromethane.
3. melting point and boiling point: the melting point and boiling point of the compound are about -25 ℃ and 225 ℃ respectively.

(S)-1-[3,5-bis (trifluoromethyl) phenyl) ethylamine has many uses:

1. synthetic intermediates: it can be used as intermediates for the synthesis of other organic compounds, such as pharmaceuticals, pesticides, etc.
2. catalyst: it can be used as a catalyst to promote a variety of organic reactions.
3. impurity detection: the compound can be used as an impurity reference material for gas chromatography analysis.

Method for preparing (S)-1-[3,5-bis (trifluoromethyl) phenyl) ethylamine:

The synthesis method of this compound is more complicated, and it is usually synthesized by the method of organic synthetic chemistry. A common method is to react terephthalic anhydride with (S)-2-phenylacetic acid ester, and then conduct fluorination reaction, amination reaction, etc. through a series of steps to finally obtain the target product.

Safety information for (S)-1-[3,5-bis (trifluoromethyl) phenyl) ethylamine:

The specific toxicity and harmfulness of this compound is not clear, so it is necessary to follow safe operating procedures during use. Avoid contact with skin and eyes, and make sure to operate in a well-ventilated area. If exposed, flush immediately with plenty of water and seek medical help. At the same time, the compound should be stored and handled properly to prevent accidents such as leakage and fire. For safety reasons, it is best to refer to the relevant safety data sheets and the safety instructions provided by the manufacturer when using the compound.

Last Update：2024-04-09 21:54:55